Posted by admin On October 2, 2008
According to a new research at Medical College of Georgia Schools of Medicine and Graduate Studies it has been found that the cancer cells have receptors for hormone estrogen to get nutrition and growth of themselves so due to this reason patients are provided with antiestrogen such as tamoxifen for five years to try to starve them to death, says Dr. Patricia V. Schoenlein .
But according to recent research it has been found that about 50 to 60% of women get benefit from this hormonal therapy but the rest didn’t .The research found that in remaining women cancer cells go into a safe mode which normal cells also performs when faced with starvation according to research published in the September issue of Molecular Cancer Therapeutics. Dr. Schoenlein also is reporting on the research during the 2nd World Conference on Magic Bullets (Ehrlich II) Oct. 3-5 in Nürenberg, Germany. Read the rest of this entry »
Posted by admin On September 8, 2008
According to a study it has been found that common painkillers reduces the level of PSA of man . PSA(prostate-specific antigen) is a blood biomarker which is used by physicians to test whether a person is at risk of prostate cancer. The study showed that it is helpful in reducing the risk of prostate cancer but use of painkillers as a treatment of this is not prescribed till by the authors of the study . As addressed by the authors on Sept. 8 in the journal Cancer,
“We showed that men who regularly took certain medications like aspirin and other non-steroidal anti-inflammatory drugs, or NSAIDS, had a lower serum PSA level,” these lines are said by Eric A. Singer, M.D., M.A., a urology resident at the University of Rochester Medical Center. “But there’s not enough data to say that men who took the medications were less likely to get prostate cancer. This was a limited study, and we do not know how many of those men actually got prostate cancer.”
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Posted by admin On August 8, 2008
Researchers at University of Florida College of Pharmacy have discovered a compound from the sea coast of Key Largo that inhibits growth of cancer cells in laboratory tests.The research can help in producing more effective drug for the disease .
The compound named is largazole which is derived from cyanobacteria which grows on coral reefs .The researchers produced their study at International natural products scientific meeting in Athens, Greece.The chemical structure of molecule of compound and it’s ability to inhibit cancer were reported in February in Journal of the American Chemical Society and the laboratory synthesis and description of it’s working as an anti-cancer is described on july 2.
Dr .Hendrik Luesch, Ph.D., an assistant professor in UF’s department of medicinal chemistry and the study principal investigator said that it will be exciting when a natural chemical will overcome all the chemical drugs to treat cancer .“Largazole” the name is given due to it’s structural features and Florida location .The scientists were checking the depth of seas from about 1960s but many of them loose interest because it is a very expensive and time consuming process .
Their are many common medications such as cholesterol-reducing statins and pain relivers which are produced from the products found on earth but “Largazole” is first anti cancer medical product which is approved since today .Their are almost 14 marine compounds which are under research .We know that their is a bank of medicines to be discovered under the depth of seas said “Luesch ”.
Posted by admin On August 7, 2008
Scientists at University of Manchester have made a 3D structure of Mps-1 which is a protein that regulates the number of chromosomes during cell division and can be used to prepair more effective cancer therapies .
Mps-1 belongs to family of protein namedkinases.When the subset or enzymes in these families work abnormally it leads to an outcome like cancer .There are about 500 kinases out of which only 100 are known and we have developed a 3D structure of only few out of them .Knowing structure will help in synthesizing new kinase which will prevent us from disease for example “Glivec” a kinase inhibitor for treating Leukaemia in the UK in 2001.
Mps-1 is important because it controls the number of chromosomes which is vital cause of cancer .The structure is developed by Dr Patrick Eyers and his team, including Hong Kong-born PhD student Matthew Chu by usind a “super microscope ” which uses Diamond Light synchrotron .
Read the rest of this entry »
According to a new research at Medical College of Georgia Schools of Medicine and Graduate Studies it has been found that the cancer cells have receptors for hormone estrogen to get nutrition and growth of themselves so due to this reason patients are provided with antiestrogen such as tamoxifen for five years to try to starve them to death, says Dr. Patricia V. Schoenlein .
